BioXclude is a minimally manipulated allograft amnion chorion tissue for use as a wound covering in dental surgery. Since its introduction in 2010, Snoasis Medical has distributed over 70,000 grafts of BioXclude. This allograft represents a paradigm shift in regenerative technology. Its unique physical and biological properties provide the benefits of a growth factor and an occlusive barrier.
Growth Factor Properties
BioXclude has been shown to contain over 250 biological factors, extracellular matrix (ECM) proteins, cytokines, interleukins, and tissue inhibitors of metalloproteinase (TIMP), known to play a role in wound healing and reducing inflammation1–4. In vitro, in vivo, and clinical research demonstrate the following benefits:1-3,5-9
- Rapid wound closure when left exposed
- Cellular occlusive with rapid sealing of protected space
- Hastens flap reattachment
- Allows for rapid vascular growth
- Shown to recruit mesenchymal stem cells
- Suppresses inflammation
Occlusive Barrier Properties
The physical properties of BioXclude allow clinicians to avoid many of the drawbacks associated with traditional collagen and synthetic membranes, which can help simplify the procedure, allow for less invasive surgery, and reduced chair time.5,7,10
The unique biologic and physical properties of amnion and amnion chorion (BioXclude) allograft allow it to be used as a wound covering for a multitude of dental implant / periodontal / oral maxillofacial applications which include5, 9, 11-17:
Sizing, Storage and Ordering
Using a larger piece makes placement much easier as it can fold over itself and/or multiple pieces overlap one another. The allograft also contains biological factors to aid healing. For these reasons, clinicians are encouraged to order larger sizes of BioXclude than they would when purchasing a traditional barrier membrane. BioXclude contains biological factors to aid healing. For this reason, and because it is thin, adaptable and excess material can be folded onto itself, clinicians are encouraged to use the entire piece, or in some cases, a bigger piece depending on the procedure. BioXclude is for single use only and is available in six sizes.
|8mm x 8mm
12mm x 12mm
10mm x 20mm
15mm x 20mm
15mm x 25mm
20mm x 30mm
Handling of the membrane is a bit tricky but it is a great product for GBR procedures as a secondary membrane if primary closure is not possible. I have used it by itself as socket preservation and cases with missing buccal plate and it does work well. Great customer service and fast shipment. Thank you.